The positive effect of Contractubex® Gel on scarring and its good tolerability have been shown in various studies.
A large-scale observational study involving 1,268 patients who had both fresh and older scars showed that an improvement in scar condition and redness was possible within 2-3 months of 2x daily application of Contractubex®. More than 80% of doctors and patients rated the effect of the treatment on scarring as good or very good. (1)
Another clinical trial examined the effect of Contractubex® Gel in 107 patients who had a tattoo removed by laser treatment. Laser treatments are known to cause scarring. In the group that applied Contractubex® Gel between treatments after wound closure, scars were found to form less frequently. (2)
A combination therapy of Contractubex® Gel with therapeutic ultrasound* was examined in an observational study of 35 patients. In this combined treatment, Contractubex® gel was introduced into the scar tissue with the aid of ultrasonic waves. Within five weeks of daily application of Contractubex® Gel as well as supplementary treatment every third day with Contractubex® Gel plus therapeutic ultrasound, the overall result improved. More than 80% of the patients and the treating physician described the success of the treatment as well as skin tolerability as good or very good. (3)
A clinical trial examined the effect on scarring after heart surgery in children and adolescents aged 1 to 18 years. After six months, the group treated with Contractubex® Gel developed significantly less conspicuous scarring than the untreated group. Even after six further months without treatment, this significant difference between the two groups remained. (4)
(1) Willital, G.H. and J. Simon, Efficacy of Early Initiation of a Gel Containing Extractum Cepae, Heparin, and Allantoin for Scar Treatment: An Observational, Noninterventional Study of Daily Practice. J Drugs Dermatol, 2013. 12(1): p. 38-42
(2) Ho, W.S., et al., Use of onion extract, heparin, allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized controlled trial. Dermatol.Surg., 2006. 32(7): p. 891-896
(3) Danneberg, D., Narbenspezialgel- rasche Effekte unter therapeutischem Ultraschall: Ergebnisse einer monozentrischen Untersuchung (Scarring special gel – rapid effects with therapeutic ultrasound: results from a monocentric study). Kosmetische Medizin – Cosmetic Medicine, 2007. 28(3).
(4) Maragakis, M., et al. Possibilities of scar treatment after thoracic surgery. Drugs Exptl. Cin. Res. XXI(5) 199-206 (1995)
* Therapeutic ultrasound should only be used by qualified personnel. The treatment is offered by doctors such as dermatologists or also by physiotherapists.
